Ultrathin Polymer Membranes with Patterned, Micrometric Pores for Organs-on-Chips

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Phase separation of ultrathin polymer-blend films on patterned substrates

The phase separation of ultrathin polymer-blend films of polystyrene and polybutadiene on microcontact printed alkanethiol patterns with hydrophobic and hydrophilic end groups (2CH3 and 2COOH! is investigated by atomic force microscopy. Simulations suggest that the phase-separation morphology can be controlled through patterns that modulate the polymer-surface interaction, and this concept is v...

متن کامل

The Effect of the Pore Entrance on Particle Motion in Slit Pores: Implications for Ultrathin Membranes

Membrane rejection models generally neglect the effect of the pore entrance on intrapore particle transport. However, entrance effects are expected to be particularly important with ultrathin membranes, where membrane thickness is typically comparable to pore size. In this work, a 2D model was developed to simulate particle motion for spherical particles moving at small Re and infinite Pe from ...

متن کامل

Polymer translocation through nano-pores in vibrating thin membranes

Polymer translocation is a promising strategy for the next-generation DNA sequencing technologies. The use of biological and synthetic nano-pores, however, still suffers from serious drawbacks. In particular, the width of the membrane layer can accommodate several bases at the same time, making difficult accurate sequencing applications. More recently, the use of graphene membranes has paved th...

متن کامل

Ultrathin, freestanding, stimuli-responsive, porous membranes from polymer hydrogel-brushes.

The fabrication of freestanding, sub-100 nm-thick, pH-responsive hydrogel membranes with controlled nano-morphology, based on modified poly(hydroxyethyl methacrylate) (PHEMA) is presented. Polymer hydrogel-brush films were first synthesized by surface-initiated atom transfer radical polymerization (SI-ATRP) and subsequently detached from silicon substrates by UV-induced photo-cleavage of a spec...

متن کامل

3D Printing of Organs-On-Chips

Organ-on-a-chip engineering aims to create artificial living organs that mimic the complex and physiological responses of real organs, in order to test drugs by precisely manipulating the cells and their microenvironments. To achieve this, the artificial organs should to be microfabricated with an extracellular matrix (ECM) and various types of cells, and should recapitulate morphogenesis, cell...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: ACS Applied Materials & Interfaces

سال: 2016

ISSN: 1944-8244,1944-8252

DOI: 10.1021/acsami.6b05754